In functional medicine, it's recognized that cardiometabolic disease is largely a result of poor lifestyle and dietary choices.And reversing cardiometabolic dysfunction for the majority ofthe population can be accomplished by implementing appropriate signals from food, lifestyle and physical activity. Because of this, cardiometabolic conditions are often not given priority in functional medicine when compared to gut or autoimmune treatments. However, given the difficulty in achieving long term behavior change, implementing targeted cost effective supplementation is vital for high risk CM patients looking to avoid pharmaceutical therapy and subsequent nutrient deficiencies and side effects.